Information about the research group

Head of the Laboratory: Zora Mělková, MD, PhD (zora.melkova@lf1.cuni.cz, tel. +420 224 968 507).

The focus of the Virology lab research consists in the studies of interactions of viruses with the host. We have an extensive experience with poxviruses, specifically vaccinia virus, the smallpox vaccine. Lately, we have been exploring the role of redox stress, induced namely by heme arginate (Normosang) and disulfiram (Antabus), in HIV-1 latency reversal and cure. We are also studying antiviral and immune-modulating properties of heme arginate and other agents active against SARS-CoV-2. Education of postgraduate and magister students and the support of the work on their theses constitute an inherent part of the lab focus.

Website of the research group: https://nolab.lf1.cuni.cz/en